Item Type | Name |
Concept
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Amino Acid Sequence
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Concept
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Repetitive Sequences, Amino Acid
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Academic Article
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Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
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Academic Article
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Studies on the metabolism and biological function of APLP2.
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Academic Article
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The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry.
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Academic Article
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Identification and characterization of a mouse homologue of the spinal muscular atrophy-determining gene, survival motor neuron.
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Academic Article
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Genetic neurodegenerative diseases: the human illness and transgenic models.
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Academic Article
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Beta-amyloid precursor protein cleavage by a membrane-bound protease.
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Academic Article
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Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing.
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Academic Article
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Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?
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Academic Article
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Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains.
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Academic Article
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Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC).
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Academic Article
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Secretion of the beta/A4 amyloid precursor protein. Identification of a cleavage site in cultured mammalian cells.
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Academic Article
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Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid beta-protein precursor-like protein-2.
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Academic Article
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Amyloid precursor-like protein 2 (APLP2) is modified by the addition of chondroitin sulfate glycosaminoglycan at a single site.
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Academic Article
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Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain.
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Academic Article
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Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail.
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Academic Article
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Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.
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Academic Article
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Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of ?-secretase using synthetic antibodies.
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Academic Article
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Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons.
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Academic Article
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Metabolism of the amyloid precursor-like protein 2 in MDCK cells. Polarized trafficking occurs independent of the chondroitin sulfate glycosaminoglycan chain.
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Academic Article
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Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function.
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Academic Article
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Metabolism of the "Swedish" amyloid precursor protein variant in Madin-Darby canine kidney cells.
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Academic Article
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Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor.
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Academic Article
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cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.
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Academic Article
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APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.
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Academic Article
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The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage.
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Academic Article
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Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).
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Academic Article
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In vivo discrimination among beta-tubulin isotypes: selective degradation of a type IV beta-tubulin isotype following overexpression in cultured animal cells.
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Academic Article
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Novel regulation of chondroitin sulfate glycosaminoglycan modification of amyloid precursor protein and its homologue, APLP2.
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Academic Article
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Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity.
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Academic Article
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The topology of pen-2, a ?-secretase subunit, revisited: evidence for a reentrant loop and a single pass transmembrane domain.
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Academic Article
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Evidence That the "Lid" Domain of Nicastrin Is Not Essential for Regulating ?-Secretase Activity.
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